Investigations in food, building, cooking, gardening and other stuff as they come up. Curiosity is ENOUGH!
Wednesday, November 30, 2011
Where are all the science majors?
The New York Times recently published an article titled:
Labels:
Science majors are quitting
Monday, November 28, 2011
10 Things to know about the seasonal flu vaccine - (WITH references)
Here are ten things to know about the seasonal
trivalent influenza vaccine.
There is a new intradermal product in the mix. I actually got this along with my office mates. I LOVE it! No issues. Some of my office mate had some itching and swelling, just localized reactions. I had NO issues. I can see this would be a great alternative for those who had "needle phobia". It's just a little skin puncture. Easy.
(1) The H1N1 (derived from the pandemic 2009 influenza virus) and H3N2 A antigens and the B antigen are the same as last year. Essentially, it's the same vaccine we got last year.
(2) The Advisory Committee for Immunization Practices (ACIP) recommends vaccination for everyone six months of age and older, including pregnant women, without a specific contraindication.
(3) Protective serum antibody levels are reached in adults about 2 weeks post-vaccination and persist for at least 6-8 months.
(4) The vaccine should be offered as soon as it is available until the end of the flu season (May).
(5) FluMist is a cold-attenuated live virus vaccine approved only for healthy non-pregnant persons 2-49 years old. FluMist seems to be more effective than the IM vaccine in children whereas the converse is generally true in adults.
(6) FluMist recipients may shed virus for a few days after vaccination, but person-to-person transmission has been rare and vaccine virus is unlikely to cause serious disease (which has never been reported) since it cannot replicate above 37 degrees C. Nonetheless, FluMist recipients should avoid close contact with severely immunocompromised persons for 7 days after vaccination.
(7) Intradermal administration theoretically improves immunogenicity because of the high vascularity and large concentration of antigen-presenting cells in the dermis. Fluzone Intradermal is 0.1 ml (not 0.5 ml) per dose, is injected through a shorter needle, and only has 9 mcg of influenza hemagglutinin antigen from each strain (the usual is 15 mcg). Limited data indicate immune response comparable to the IM vaccine, but no published studies on the clinical efficacy of the vaccine against infection or illness are available. (we'll see how I do). The last time I had the REAL flu I felt like I was going to die....my skin hurt, my hair hurt. After that learning experience....I always get the shot.
(8) Fluzone High-Dose, an alternative to the standard IM vaccine for patients 65 and older, contains 60 mcg of hemagglutinin antigen from each strain (4x the usual). It causes more injection-site reactions than the standard vaccine (as does Fluzone Intradermal, by the way).
(9) Influenza vaccination has very rarely been associated with Guillain-Barre syndrome, but so has influenza infection itself.
(10) Dosing of IM vaccine: 0.5 ml x1 if 3 years or older, 0.25 ml x1 if 6-35 months old. Children <9 years old being vaccinated for the first time should receive two doses separated by at least 4 weeks (second dose given before December if possible). Since this year's vaccine is the same as last year, children <9 who received only one dose of vaccine last year require only one dose this year (normally they would receive two). Dosing of FluMist: 0.1 ml in each nostril x1; children 2-8 years being vaccinated for the first time should do this twice (separated by at least 4 weeks).
(11) BOTTOM LINE....GO GET YOUR FLU SHOT/INTERDERMAL INJECTION.
REFERENCE
Influenza vaccine for 2011-2012. Med Letter Drugs Ther 2011; 53: 81-83.
Labels:
seasonal flu vaccine
Sunday, November 27, 2011
Turkey leftovers? My favorite = Turkey pot pie
I grew up (as many of us did) with frozen chicken/turkey pot pies from Swanson. I know, I know.....we really don't like to admit it....but we did. I can remember buying several while in college and eating them during finals week. Very comforting but.....NOT very good for me dietary wise.
I STILL love pot pies. The good news is that they are very easy to make and now with leftovers of the turkey kind.....all the ingredients are just waiting. Here's my recipe:
First - decide what kind of crust you want. Do you have flour, fat (butter, shortening, etc) and water....pie crust works wonderfully. If you have a sheet of puff pastry in your freezer (who doesn't, right?) use this. Do you have leftover potatoes? These are made to order! Since this is about leftovers...lets assume this is what we'll use.
For the filling:
Saute onion, celery, and any vegetable you have in a bit of olive oil until just brown. I love carrots so add these, diced. Have any leftover vegetables? (Squash, peas, beans, etc) add them now. Add cubed turkey and heat through. Leftover gravy? Add this now. No leftover gravy? Don't let this stop you....use chicken stock. White wine is awesome too!
Thin a bit or cook down to a nice sauce. If you want to add any frozen vegis....now is the time. Have leftover cream or half and half....add if you want, depending on your cholesterol tolerance.
When it's nice and bubbly, add to ramekins for small pies or a baking dish appropriate to how much filling you have.
Top with your topping, puff pastry, mashed potatoes, crust. I like to sprinkle with cheese, just a bit. Use what you have. Tuck in the edges. Cut slits in the top if using crust to let the steam out.
Pop into a 375 degree oven and bake until the top is golden brown. The filling is already cooked so it just needs to bubble to be ready. DON'T forget to put them on a baking sheet to collect the bubbled over filling. They can make a HUGE mess in your oven.
Let it cool so you can eat it. Add a salad......probably leftover too, right? Mmmmmmm!
So, these are soooo much better than those frozen pies you have NO idea! Here's something good too......more than you can eat at one sitting? FREEZE THEM! Wrap in foil and plastic wrap and then in a zip-lock bag. JUST the thing during finals week-----again!
I STILL love pot pies. The good news is that they are very easy to make and now with leftovers of the turkey kind.....all the ingredients are just waiting. Here's my recipe:
First - decide what kind of crust you want. Do you have flour, fat (butter, shortening, etc) and water....pie crust works wonderfully. If you have a sheet of puff pastry in your freezer (who doesn't, right?) use this. Do you have leftover potatoes? These are made to order! Since this is about leftovers...lets assume this is what we'll use.
For the filling:
Saute onion, celery, and any vegetable you have in a bit of olive oil until just brown. I love carrots so add these, diced. Have any leftover vegetables? (Squash, peas, beans, etc) add them now. Add cubed turkey and heat through. Leftover gravy? Add this now. No leftover gravy? Don't let this stop you....use chicken stock. White wine is awesome too!
Thin a bit or cook down to a nice sauce. If you want to add any frozen vegis....now is the time. Have leftover cream or half and half....add if you want, depending on your cholesterol tolerance.
When it's nice and bubbly, add to ramekins for small pies or a baking dish appropriate to how much filling you have.
Top with your topping, puff pastry, mashed potatoes, crust. I like to sprinkle with cheese, just a bit. Use what you have. Tuck in the edges. Cut slits in the top if using crust to let the steam out.
Pop into a 375 degree oven and bake until the top is golden brown. The filling is already cooked so it just needs to bubble to be ready. DON'T forget to put them on a baking sheet to collect the bubbled over filling. They can make a HUGE mess in your oven.
The best part of leftovers! |
So, these are soooo much better than those frozen pies you have NO idea! Here's something good too......more than you can eat at one sitting? FREEZE THEM! Wrap in foil and plastic wrap and then in a zip-lock bag. JUST the thing during finals week-----again!
Labels:
turkey pot pie
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